Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPER1 | Q99527 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611672 | 0.91 | GPER1 (0.54) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL12722292 | 0.90 | GPER1 (0.58) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL917263 | 0.80 | GPER1 (0.57) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL916034 | 0.79 | GPER1 (0.56) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL15107073 | 0.78 | GPER1 (0.60) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL12722694 | 0.78 | L3MBTL1 (0.57) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL12700959 | 0.77 | L3MBTL1 (0.78) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL916068 | 0.75 | GPER1 (0.62) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL915699 | 0.73 | GPER1 (0.52) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL916384 | 0.73 | GPER1 (0.51) | GPER1L3MBTL1GPR183NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019180-A2 | COMPOUNDS FOR BINDING TO ERALPHA/BETA AND GPR30, METHODS OF TREATING DISEASE STATES AND CONDITIONS MEDIATED THROUGH THESE RECEPTORS AND IDENTIFICATION THEREOF | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2007-02-15 | — | — | WO | disclosed |