Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | GPER1 | Q99527 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611897 | 0.90 | MAPT (0.47) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL916386 | 0.86 | L3MBTL1 (0.65) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL18130926 | 0.86 | L3MBTL1 (0.65) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL14611899 | 0.85 | MAPT (0.43) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL12700960 | 0.75 | L3MBTL1 (0.64) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL12701119 | 0.73 | MAPT (0.81) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL21105517 | 0.70 | L3MBTL1 (0.57) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL20506686 | 0.70 | L3MBTL1 (0.57) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL24203417 | 0.68 | MAPT (1.00) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL916391 | 0.68 | MAPT (1.00) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019180-A2 | COMPOUNDS FOR BINDING TO ERALPHA/BETA AND GPR30, METHODS OF TREATING DISEASE STATES AND CONDITIONS MEDIATED THROUGH THESE RECEPTORS AND IDENTIFICATION THEREOF | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2007-02-15 | — | — | WO | disclosed |