Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.46 |
| ▸ | FABP7 | O15540 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16360194 | 0.99 | KMT2A (0.54) | KMT2AFABP5FABP7TNFDGKA | |
| SCHEMBL10071038 | 0.95 | KMT2A (0.50) | KMT2AFABP5FABP7TNFEPHX2 | |
| SCHEMBL4947412 | 0.91 | KMT2A (0.57) | KMT2ATNFDGKAEPHX2TLR2 | |
| SCHEMBL14759878 | 0.91 | KMT2A (0.60) | KMT2AFABP5FABP7TNFEPHX2 | |
| SCHEMBL29779340 | 0.89 | KMT2A (0.50) | KMT2AFABP5FABP7TNFEPHX2 | |
| SCHEMBL30781736 | 0.89 | KMT2A (0.50) | KMT2AFABP5FABP7TNFEPHX2 | |
| SCHEMBL47693 | 0.89 | KMT2A (0.50) | KMT2AFABP5FABP7TNFEPHX2 | |
| SCHEMBL3623157 | 0.89 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL5497604 | 0.86 | KMT2A (0.55) | KMT2AFABP5FABP7TNFEPHX2 | |
| SCHEMBL14612136 | 0.85 | KMT2A (0.48) | KMT2AFABP5FABP7TNFTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016188835-A1 | SUPPORTS FOR MEMBRANE ENHANCED PEPTIDE SYNTHESIS | LONZA LTD (CH) | 2016-12-01 | — | — | WO | disclosed |
| US-7179918-B2 | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis | AGOURON PHARMACEUTICALS, INC. (US) | 2007-02-20 | — | — | US | disclosed |