⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851485 | 0.86 | KDM4E (0.30) | — | |
| SCHEMBL5904175 | 0.75 | CRBN (0.37) | — | |
| SCHEMBL1971796 | 0.74 | CDA (0.33) | — | |
| SCHEMBL306969 | 0.73 | KDM4E (0.34) | — | |
| SCHEMBL27755656 | 0.71 | BRD4 (0.35) | — | |
| SCHEMBL4500931 | 0.70 | GAA (0.35) | — | |
| SCHEMBL10772828 | 0.70 | — | — | |
| SCHEMBL28410669 | 0.69 | — | — | |
| SCHEMBL232289 | 0.69 | — | — | |
| SCHEMBL8875695 | 0.68 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006331-B2 | Therapeutic compounds and methods | GENENTECH, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| EP-4370130-A1 | THERAPEUTIC COMPOUNDS AND METHODS | Genentech, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| US-11987572-B2 | Therapeutic compounds and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-05-21 | — | — | US | disclosed |
| EP-4362985-A1 | OLIGONUCLEOTIDE CONJUGATES TARGETED TO THE TRANSFERRIN RECEPTOR | Denali Therapeutics Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2024086161-A2 | EPHA2 TARGETING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-25 | — | — | WO | disclosed |
| US-20240109872-A1 | CONTRACEPTIVE COMPOUNDS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-04-04 | — | — | US | disclosed |
| CN-117693367-A | Oligonucleotide conjugates targeting transferrin receptor | 戴纳立制药公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117642170-A | Therapeutic compounds and methods | 基因泰克公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2024044375-A2 | ANTIVIRAL COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20240051938-A1 | SELECTIVE BRD4-DEGRADER MOLECULES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-02-15 | — | — | US | disclosed |
| US-20200255454-A1 | SEPARATIONS USING BORON CONTAINING HYDROCARBON SPONGES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2020-08-13 | — | — | US | disclosed |
| WO-2019240884-A9 | COMPOSITIONS FOR CHELATING METALS AT LOW TEMPERATURES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2020-02-06 | — | — | WO | disclosed |
| WO-2019046465-A2 | THERAPEUTIC INDOLES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-03-07 | — | — | WO | disclosed |
| US-20180360972-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-12-20 | — | — | US | disclosed |
| US-20180339972-A1 | LACTONE-BASED PROBES AND METHODS OF USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-11-29 | — | — | US | disclosed |
| US-20180292387-A1 | ANTIBIOTIC-BASED CONJUGATES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-10-11 | — | — | US | disclosed |
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | disclosed |
| EP-1289984-A4 | NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | DONG A PHARM CO LTD (KR) | 2004-11-24 | — | — | EP | disclosed |
| EP-1289984-A1 | NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | Dong A Pharmaceutical Co. Ltd. (KR) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001094342-A1 | NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | DONG A PHARM. CO., LTD. (KR) | 2001-12-13 | — | — | WO | disclosed |