Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PRKDC | P78527 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12385911 | 0.81 | ALDH1A1 (0.69) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL12864867 | 0.80 | MAPT (0.64) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL25998473 | 0.80 | MAPT (0.48) | ALDH1A1L3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL3723011 | 0.79 | ALDH1A1 (0.59) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9906943 | 0.79 | ALDH1A1 (0.67) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL171808 | 0.79 | MAPT (0.65) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13232531 | 0.79 | ALDH1A1 (0.54) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3885064 | 0.78 | KMT2A (0.53) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL19496762 | 0.76 | ALDH1A1 (0.51) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL12385978 | 0.76 | POLB (0.48) | ALDH1A1PRKDCL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043095-A1 | Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use | IPSEN PHARMA S.A.S. (FR) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043095-A1 | Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use | SSTR2, SSTR5, SSTR3 | ALDH1A1 812/4885PRKDC 4086/4885L3MBTL1 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.