SCHEMBL14612467

SCHEMBL14612467

INCCOc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 8/20 0.63
DRD2 P14416 7/20 0.63
DRD3 P35462 7/20 0.63
HTR1B P28222 2/20 0.63
HTR1D P28221 1/20 0.63
KCNA3 P22001 1/20 0.58
GAA P10253 1/20 0.55
MTNR1A P48039 1/20 0.53
MTNR1B P49286 1/20 0.53
RECQL P46063 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
ALDH1A1 P00352 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
NPC1 O15118 1/20 0.52
HPGD P15428 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8938905 0.81 DRD4 (0.91) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL10476759 0.79 DRD4 (0.95) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL11410999 0.78 DRD4 (0.70) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL11402571 0.77 DRD4 (0.63) DRD4DRD2DRD3HTR1BHTR1D
Hydrochloric Acid SCHEMBL8054973 0.77 DRD4 (0.91) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL11896615 0.77 DRD4 (1.00) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL28693297 0.77 DRD4 (0.63) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL595753 0.77 HTR1B (1.00) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL1488231 0.77 DRD4 (0.63) DRD4DRD2DRD3HTR1BHTR1D
SCHEMBL4867980 0.77 DRD4 (0.63) DRD4DRD2DRD3HTR1BHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3319139-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR BATTERY, AND COMPOSITION Fujifilm Corporation (JP) 2018-05-09 EP disclosed
US-20180108492-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOSITION FUJIFILM CORPORATION (JP) 2018-04-19 US disclosed
US-20070043095-A1 Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use IPSEN PHARMA S.A.S. (FR) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180108492-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOSITION SCNN1A, CRY1, NR2E3 DRD4 1256/4885DRD2 2278/4885DRD3 2179/4885
US-20070043095-A1 Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use SSTR2, SSTR5, SSTR3 DRD4 406/4885DRD2 324/4885DRD3 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.