Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19573483 | 0.91 | MC4R (0.34) | MC4RMC5RMC3RKAT2B | |
| SCHEMBL16687699 | 0.90 | MC4R (0.33) | MC4RMC5RMC3R | |
| SCHEMBL11960642 | 0.90 | HDAC1 (0.34) | MC4RMC5RMC3RPARP1 | |
| SCHEMBL11960639 | 0.88 | CHRM2 (0.38) | MC4RMC5RMC3R | |
| SCHEMBL11208 | 0.88 | MC4R (0.33) | MC4RMC5RMC3RKAT2BPARP1 | |
| SCHEMBL11960638 | 0.88 | BRD4 (0.37) | MC4RMC5RMC3R | |
| SCHEMBL20124107 | 0.88 | HDAC1 (0.34) | MC4RMC5RMC3RKAT2B | |
| SCHEMBL11960641 | 0.87 | MARS1 (0.33) | MC4RMC5RMC3R | |
| SCHEMBL11920 | 0.87 | MC4R (0.37) | MC4RMC5RMC3R | |
| SCHEMBL20124187 | 0.86 | MC4R (0.32) | MC4RMC5RMC3RPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023843-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| WO-2011047320-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |