SCHEMBL14613601

SCHEMBL14613601

Cc1ccc(Cl)cc1S(=O)(=O)N(c1ccc([C@](C)(O)C(F)(F)F)cc1)C(C)C

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5567960 0.89 HSD11B1 (1.00) HSD11B1
SCHEMBL5564601 0.89 HSD11B1 (1.00) HSD11B1
SCHEMBL5567998 0.89 HSD11B1 (1.00) HSD11B1
SCHEMBL5567765 0.80 HSD11B1 (1.00) HSD11B1
SCHEMBL5569002 0.80 HSD11B1 (1.00) HSD11B1
SCHEMBL5564463 0.80 HSD11B1 (1.00) HSD11B1
SCHEMBL5564197 0.78 HSD11B1 (1.00) HSD11B1
SCHEMBL5567768 0.78 HSD11B1 (1.00) HSD11B1
SCHEMBL5564297 0.78 HSD11B1 (1.00) HSD11B1
SCHEMBL5564561 0.78 HSD11B1 (1.00) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007013929-A1 ANILINE SULFONAMIDE DERIVATIVES AND THEIR USES AMGEN INC. (US) 2007-02-01 WO disclosed