SCHEMBL14613671

SCHEMBL14613671

CC(C)N(c1ccc(C(C)(C)O)cc1Cl)S(=O)(=O)c1ccccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5564130 0.88 HSD11B1 (0.77) HSD11B1
SCHEMBL5567765 0.76 HSD11B1 (1.00) HSD11B1
SCHEMBL5569002 0.76 HSD11B1 (1.00) HSD11B1
SCHEMBL5564463 0.76 HSD11B1 (1.00) HSD11B1
SCHEMBL4599206 0.70 HSD11B1 (0.65) HSD11B1
SCHEMBL5564195 0.69 HSD11B1 (0.82) HSD11B1
SCHEMBL14613566 0.68 HSD11B1 (0.61) HSD11B1
SCHEMBL14613568 0.68 HSD11B1 (0.79) HSD11B1
SCHEMBL2901763 0.67 HSD11B1 (1.00) HSD11B1
SCHEMBL5564297 0.67 HSD11B1 (1.00) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007013929-A1 ANILINE SULFONAMIDE DERIVATIVES AND THEIR USES AMGEN INC. (US) 2007-02-01 WO disclosed