Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486375 | 0.83 | KCNN4 (0.44) | KCNN4KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL16609226 | 0.82 | KCNN4 (0.52) | KCNN4KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6566499 | 0.82 | KCNN4 (0.52) | KCNN4KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10053574 | 0.77 | KCNN4 (0.50) | KCNN4ALDH1A1CYP2D6HSD17B10CACNA1F | |
| SCHEMBL15672754 | 0.76 | KCNN4 (0.43) | KCNN4KMT2AMAPTALDH1A1CYP2D6 | |
| SCHEMBL4857148 | 0.76 | KCNN4 (0.43) | KCNN4KMT2AMAPTALDH1A1CYP2D6 | |
| SCHEMBL225196 | 0.76 | CA12 (0.44) | KCNN4KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL7418701 | 0.76 | KCNN4 (0.35) | KCNN4KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL2552945 | 0.76 | KCNN4 (0.35) | KCNN4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL28513998 | 0.74 | KCNN4 (0.42) | KCNN4KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529047-B1 | NEW PURINE DERIVATIVES | CYCLACEL LTD (GB) | 2007-02-21 | — | — | EP | disclosed |