SCHEMBL14613992

SCHEMBL14613992

Bc1ccc(-c2nc3cc(C(=O)O)ccc3n2C2CCCC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.65
HCAR3 P49019 4/20 0.50
HSD17B10 Q99714 2/20 0.50
GAA P10253 1/20 0.50
IDH1 O75874 2/20 0.48
RPS6KB1 P23443 1/20 0.45
PTGER4 P35408 2/20 0.44
NR1H4 Q96RI1 4/20 0.43
BCAT2 O15382 1/20 0.43
VDR P11473 3/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14382664 0.93 L3MBTL1 (0.71) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL5508908 0.89 L3MBTL1 (0.67) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL14382577 0.89 L3MBTL1 (0.67) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL14382774 0.89 L3MBTL1 (0.70) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL14382666 0.89 L3MBTL1 (0.70) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL14382768 0.88 L3MBTL1 (0.65) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL14382770 0.88 L3MBTL1 (0.65) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL14613999 0.88 L3MBTL1 (0.72) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL14382762 0.88 L3MBTL1 (0.65) L3MBTL1HCAR3HSD17B10GAAIDH1
SCHEMBL27672880 0.88 L3MBTL1 (0.69) L3MBTL1HCAR3HSD17B10GAAIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070032497-A1 Fused-ring compounds and use thereof as drugs JAPAN TOBACCO INC. (JP) 2007-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032497-A1 Fused-ring compounds and use thereof as drugs HAVCR2, ZC3HAV1, HLA-C L3MBTL1 4730/4885HCAR3 1271/4885HSD17B10 280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.