Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.51 |
| ▸ | IDH1 | O75874 | 2/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.45 |
| ▸ | VDR | P11473 | 3/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613999 | 0.92 | L3MBTL1 (0.72) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL14382664 | 0.92 | L3MBTL1 (0.71) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL14382774 | 0.91 | L3MBTL1 (0.70) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL14382795 | 0.90 | L3MBTL1 (0.58) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL27574019 | 0.90 | L3MBTL1 (0.69) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL27672880 | 0.90 | L3MBTL1 (0.69) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL14382577 | 0.88 | L3MBTL1 (0.67) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL5508908 | 0.88 | L3MBTL1 (0.67) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL14382666 | 0.88 | L3MBTL1 (0.70) | L3MBTL1HSD17B10GAAHCAR3IDH1 | |
| SCHEMBL14613838 | 0.88 | L3MBTL1 (0.67) | L3MBTL1HSD17B10GAAHCAR3IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032497-A1 | Fused-ring compounds and use thereof as drugs | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032497-A1 | Fused-ring compounds and use thereof as drugs | HAVCR2, ZC3HAV1, HLA-C | L3MBTL1 4730/4885HSD17B10 280/4885GAA 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.