Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.67 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.57 |
| ▸ | CHKA | P35790 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14986322 | 0.93 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBCYP2A13KMT2A | |
| Hydrochloric Acid SCHEMBL23850789 | 0.86 | ALDH1A1 (0.85) | ALDH1A1KDM4EPOLBCYP2A13KMT2A | |
| SCHEMBL3262128 | 0.84 | ALDH1A1 (0.96) | ALDH1A1KDM4EPOLBCYP2A13KMT2A | |
| SCHEMBL16226380 | 0.84 | ALDH1A1 (0.81) | ALDH1A1KDM4EPOLBCYP2A13KMT2A | |
| SCHEMBL19562076 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBCYP2A13KMT2A | |
| SCHEMBL807350 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBCYP2A13KMT2A | |
| Hydrochloric Acid SCHEMBL7409874 | 0.81 | ALDH1A1 (0.96) | ALDH1A1KDM4EPOLBCYP2A13KMT2A | |
| SCHEMBL12993260 | 0.81 | KDM4E (0.68) | ALDH1A1KDM4EPOLBCYP2A13CHKA | |
| SCHEMBL19288785 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4EPOLBCHKAKMT2A | |
| SCHEMBL6384809 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBCYP2A13CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |