Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12992972 | 0.91 | PYCR1 (0.54) | PYCR1TAAR1AOC3ACHECARM1 | |
| SCHEMBL14174811 | 0.82 | CYP2D6 (0.54) | TAAR1ACHETSHRRECQL | |
| SCHEMBL13362520 | 0.82 | TSHR (0.45) | ACHECARM1SIGMAR1SMN1; SMN2TSHR | |
| SCHEMBL15308498 | 0.81 | PYCR1 (0.61) | PYCR1TAAR1AOC3ACHECARM1 | |
| SCHEMBL13232635 | 0.81 | TAAR1 (0.51) | TAAR1SIGMAR1TSHRRIPK1 | |
| SCHEMBL21902241 | 0.80 | CARM1 (0.62) | PYCR1TAAR1AOC3ACHECARM1 | |
| SCHEMBL16549287 | 0.80 | MEN1 (0.52) | PYCR1AOC3ACHESIGMAR1GAA | |
| SCHEMBL615516 | 0.79 | TSHR (0.65) | CARM1SIGMAR1SMN1; SMN2TSHR | |
| SCHEMBL30093221 | 0.79 | PYCR1 (0.67) | PYCR1TAAR1AOC3ACHEGAA | |
| SCHEMBL14149935 | 0.79 | PYCR1 (0.58) | PYCR1TAAR1AOC3ACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |