Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614579 | 0.84 | MEN1 (0.50) | MEN1RAB9AKMT2AIRAK4ASIC3 | |
| SCHEMBL21116000 | 0.82 | IRAK4 (0.48) | IRAK4TRPV3CNR2CNR1 | |
| SCHEMBL2609332 | 0.81 | KMT2A (0.60) | MEN1RAB9AKMT2AASIC3TRPV3 | |
| SCHEMBL15868176 | 0.80 | IRAK4 (0.40) | MEN1KMT2AIRAK4HTR2AALDH1A1 | |
| SCHEMBL12137374 | 0.78 | MEN1 (0.56) | MEN1RAB9AKMT2AIRAK4ASIC3 | |
| SCHEMBL14108546 | 0.78 | KMT2A (0.56) | MEN1RAB9AKMT2AASIC3TRPV3 | |
| SCHEMBL16768767 | 0.78 | MEN1 (0.56) | MEN1RAB9AKMT2AIRAK4ASIC3 | |
| SCHEMBL27651071 | 0.78 | KMT2A (0.56) | MEN1RAB9AKMT2AASIC3TRPV3 | |
| SCHEMBL15883189 | 0.78 | KMT2A (0.43) | MEN1RAB9AKMT2AIRAK4ASIC3 | |
| SCHEMBL15883118 | 0.77 | KDM4E (0.41) | MEN1RAB9AKMT2AIRAK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |