Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 2/20 | 0.34 |
| ▸ | PGK2 | P07205 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447422 | 0.87 | IRAK4 (0.48) | IRAK4MAP4K4ALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL23226823 | 0.85 | KCNH2 (0.40) | IRAK4MAP4K4CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8980617 | 0.82 | CYP2D6 (0.42) | IRAK4TAAR1SLC6A4CYP2D6CYP3A4 | |
| SCHEMBL14614690 | 0.80 | MEN1 (0.52) | IRAK4ALDH1A1HTR2AHSD17B10MEN1 | |
| SCHEMBL15883118 | 0.75 | KDM4E (0.41) | IRAK4ALDH1A1SLC6A4GLAALOX15 | |
| SCHEMBL125581 | 0.75 | SLC6A2 (0.47) | ALDH1A1SLC6A4CYP2D6CYP3A4CHRM2 | |
| SCHEMBL13081517 | 0.75 | SLC6A2 (0.47) | ALDH1A1SLC6A4CYP2D6CYP3A4CHRM2 | |
| SCHEMBL12310369 | 0.75 | SLC6A2 (0.47) | ALDH1A1SLC6A4CYP2D6CYP3A4CHRM2 | |
| SCHEMBL21116000 | 0.74 | IRAK4 (0.48) | IRAK4MAP4K4 | |
| Hydrochloric Acid SCHEMBL28642995 | 0.73 | SLC6A2 (0.45) | ALDH1A1TAAR1SLC6A4CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140194627-A1 | Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194627-A1 | Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | ZRANB2, ZKSCAN2, SLC39A3 | IRAK4 3660/4885PGK1 1974/4885PGK2 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.