Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14585959 | 0.92 | KDM4E (0.51) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| Bicarbonate SCHEMBL11114446 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL14585963 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL17453757 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL7257590 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| Bicarbonate SCHEMBL10377652 | 0.82 | ALDH1A1 (0.67) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10961565 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL14585956 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| Bicarbonate SCHEMBL10873564 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10818438 | 0.81 | KDM4E (0.78) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176206-B2 | Antibiotics | DAR AL DAWA DEVELOPMENT AND INVESTMENT CO. (JO) | 2007-02-13 | — | — | US | disclosed |