⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616003 | 1.00 | — | — | |
| SCHEMBL19292174 | 1.00 | — | — | |
| SCHEMBL14037839 | 1.00 | — | — | |
| SCHEMBL12631472 | 0.88 | — | — | |
| SCHEMBL22149365 | 0.85 | — | — | |
| SCHEMBL23252817 | 0.81 | — | — | |
| SCHEMBL6258134 | 0.81 | — | — | |
| SCHEMBL3482203 | 0.81 | — | — | |
| SCHEMBL20848081 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL18800548 | 0.79 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037206-A1 | Polypeptide of given sequence and antibodies that bind; gene expression; treatment of muscular dystrophy and cystic fibrosis | HUMAN GENOME SCIENCES, INC. | 2007-02-15 | — | — | US | disclosed |