⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022791 | 1.00 | — | — | |
| SCHEMBL5654280 | 1.00 | — | — | |
| SCHEMBL13895038 | 0.89 | EPHX2 (0.32) | — | |
| SCHEMBL20288193 | 0.85 | — | — | |
| SCHEMBL12869749 | 0.82 | — | — | |
| SCHEMBL21482784 | 0.82 | — | — | |
| SCHEMBL18434946 | 0.82 | — | — | |
| SCHEMBL22108021 | 0.80 | — | — | |
| SCHEMBL19912843 | 0.80 | — | — | |
| SCHEMBL292099 | 0.78 | NOS1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270734-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2023-08-31 | — | — | US | disclosed |
| US-20070037206-A1 | Polypeptide of given sequence and antibodies that bind; gene expression; treatment of muscular dystrophy and cystic fibrosis | HUMAN GENOME SCIENCES, INC. | 2007-02-15 | — | — | US | disclosed |