Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764739 | 0.87 | TNFRSF1A (0.65) | TNFRSF1AF3MAPTMAOBRAB9A | |
| SCHEMBL22198101 | 0.78 | PTGS1 (0.65) | TNFRSF1AMAPTMAOBRAB9AMAOA | |
| SCHEMBL13769218 | 0.77 | ABCG2 (0.46) | TNFRSF1AMAPTMAOBRAB9AMAOA | |
| SCHEMBL11096408 | 0.76 | TNFRSF1A (0.78) | TNFRSF1AF3MAPTMAOBRAB9A | |
| SCHEMBL11096416 | 0.76 | TNFRSF1A (0.78) | TNFRSF1AF3MAPTMAOBRAB9A | |
| SCHEMBL15166601 | 0.72 | MAPT (0.52) | TNFRSF1AMAPTMAOBRAB9AMAOA | |
| SCHEMBL570958 | 0.72 | MAPT (0.52) | TNFRSF1AMAPTMAOBRAB9AMAOA | |
| SCHEMBL7551932 | 0.71 | TNFRSF1A (0.62) | TNFRSF1AF3MAPTMAOBRAB9A | |
| SCHEMBL14224729 | 0.71 | SMN1; SMN2 (0.46) | MAPTRAB9APOLBGABBR2GABBR1 | |
| SCHEMBL13359041 | 0.71 | MAPT (0.66) | F3MAPTMAOBRAB9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | PSEN1, BACE1, PSEN2 | TNFRSF1A 2548/4885F3 2492/4885MAPT 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.