Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | RGS12 | O14924 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175613 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP3A4CYP1A2CYP2C9MEN1 | |
| SCHEMBL8260206 | 0.81 | MEN1 (0.53) | SMN1; SMN2CYP3A4CYP1A2CYP2C9MEN1 | |
| SCHEMBL10458268 | 0.77 | CA2 (0.61) | SMN1; SMN2CYP1A2CYP2C9MAPTALDH1A1 | |
| SCHEMBL805444 | 0.77 | CA2 (0.45) | SMN1; SMN2CYP3A4CYP1A2CYP2C9MEN1 | |
| SCHEMBL805430 | 0.75 | NR5A2 (0.48) | SMN1; SMN2CYP3A4CYP1A2CYP2C9MEN1 | |
| SCHEMBL12240426 | 0.75 | CA2 (0.59) | SMN1; SMN2CYP1A2CYP2C9MAPTALDH1A1 | |
| SCHEMBL2811722 | 0.75 | CA2 (0.65) | SMN1; SMN2CYP1A2CYP2C9MAPTALDH1A1 | |
| SCHEMBL12651295 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP1A2CYP2C9MEN1MAPT | |
| SCHEMBL13178842 | 0.74 | CA2 (0.42) | SMN1; SMN2CYP1A2CYP2C9MEN1MAPT | |
| SCHEMBL13299510 | 0.74 | CA2 (0.42) | SMN1; SMN2CYP3A4CYP1A2CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096894-A1 | Anti-Bacterial Compounds | ASTON UNIVERSITY (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096894-A1 | Anti-Bacterial Compounds | MRPL21, PGLS, FOSB | SMN1; SMN2 4485/4885CYP3A4 3723/4885CYP1A2 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.