Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CASR | P41180 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554431 | 0.91 | HPGD (0.57) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL14616757 | 0.85 | HPGD (0.64) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL5374411 | 0.82 | HPGD (1.00) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL2555588 | 0.82 | HPGD (0.49) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL14576973 | 0.81 | PTGER4 (0.61) | HPGDKMT2APTGER4 | |
| SCHEMBL14575950 | 0.78 | RIPK2 (0.49) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL14575975 | 0.78 | RIPK2 (0.43) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL2554274 | 0.78 | RIPK2 (0.45) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL14576869 | 0.77 | KDM4E (0.49) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR | |
| Hydrochloric Acid SCHEMBL7178948 | 0.76 | HPGD (0.68) | HPGDKDM4ESMN1; SMN2ALDH1A1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018039-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018039-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | MAP3K19, MAP3K20, MAP3K3 | HPGD 3449/4885KDM4E 764/4885SMN1; SMN2 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.