Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616791 | 0.89 | RIPK2 (0.43) | RIPK2MAPK1ALOX15NPC1POLB | |
| SCHEMBL14616792 | 0.88 | RIPK2 (0.43) | RIPK2MAPK1ALOX15NPC1POLB | |
| SCHEMBL14616796 | 0.88 | RIPK2 (0.53) | RIPK2MAPK1ALOX15NPC1POLB | |
| SCHEMBL14616831 | 0.86 | RIPK2 (0.47) | RIPK2MAPK1ALOX15NPC1POLB | |
| SCHEMBL14616834 | 0.86 | RIPK2 (0.44) | RIPK2MAPK1ALOX15NPC1POLB | |
| SCHEMBL14616801 | 0.85 | RIPK2 (0.49) | RIPK2NPC1RAB9APTGER4HSD17B10 | |
| SCHEMBL14575762 | 0.85 | ALOX15 (0.36) | RIPK2MAPK1ALOX15NPC1POLB | |
| SCHEMBL14616800 | 0.83 | RIPK2 (0.53) | RIPK2MAPK1ALOX15NPC1POLB | |
| SCHEMBL14616799 | 0.83 | RIPK2 (0.51) | RIPK2PTGER4HSD17B10KDM4ERECQL | |
| SCHEMBL14616835 | 0.83 | RIPK2 (0.41) | RIPK2MAPK1ALOX15NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018039-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2013-01-17 | — | — | US | disclosed |
| US-20130018039-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018039-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | MAP3K19, MAP3K20, MAP3K3 | RIPK2 255/4885MAPK1 74/4885ALOX15 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.