Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | GLS | O94925 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462200 | 1.00 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL30610393 | 1.00 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL1461693 | 1.00 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL28130578 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPK1LMNAMAPT | |
| SCHEMBL493954 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL12175042 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL1286155 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL12175072 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL10299137 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRHSD17B10GLS | |
| SCHEMBL628737 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRHSD17B10GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003665-A | Synthesis process of N, N-diethyl-2-hydroxy-2-phenylacetamide | 百新(北京)药业科技有限责任公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116554940-B | Oily corrosion inhibitor and preparation method thereof | 江苏太湖新材料控股有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-116554940-A | Oily corrosion inhibitor and preparation method thereof | 江苏太湖新材料技术研发有限公司 | 2023-08-08 | — | — | CN | claimed |
| EP-1556417-B1 | RACEMOSELECTIVE PREPARATION OF BRIDGED METALLOCENE COMPLEXES HAVING UNSUBSTITUTED OR 2-SUBSTITUTED INDENYL LIGANDS | BASELL POLYOLEFINE GMBH (DE) | 2009-06-10 | — | — | EP | claimed |
| US-7358381-B2 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | BASELL POLYOLEFINE GMBH (DE) | 2008-04-15 | — | — | US | claimed |
| EP-1554297-B1 | RACEMOSELECTIVE SYNTHESIS OF RAC-DIORGANOSILYLBIS(2-METHYLBENZO¬E|INDEYL) ZIRCONIUM COMPONDS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-12 | — | — | EP | claimed |
| US-20060111527-A1 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | EQUISTAR CHEMICALS, LP | 2006-05-25 | — | — | US | claimed |
| EP-1556417-A2 | RACEMOSELECTIVE PREPARATION OF BRIDGED METALLOCENE COMPLEXES HAVING UNSUBSTITUTED OR 2-SUBSTITUTED INDENYL LIGANDS | Basell Polyolefine GmbH (DE) | 2005-07-27 | — | — | EP | claimed |
| WO-2004037834-A2 | RACEMOSELECTIVE PREPARATION OF BRIDGED METALLOCENE COMPLEXES HAVING UNSUBSTITUTED OR 2-SUBSTITUTED INDENYL LIGANDS | BASELL POLYOLEFINE GMBH (DE) | 2004-05-06 | — | — | WO | claimed |
| US-5206363-A | PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF 5-HETEROARYL-1,3,4-THIADIAZINONES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | claimed |
| EP-0051190-A2 | N-(amino(or hydroxy) phenethyl)-1,2,3,4-tetrahydroisoquinolines, precursors thereof, and methods of preparation | PENNWALT CORPORATION (US) | 1982-05-12 | — | — | EP | claimed |
| CN-117384217-A | Preparation method of composite phosphorus-free water treatment corrosion inhibitor | 广东天祺环保科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117003665-A | Synthesis process of N, N-diethyl-2-hydroxy-2-phenylacetamide | 百新(北京)药业科技有限责任公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116554940-B | Oily corrosion inhibitor and preparation method thereof | 江苏太湖新材料控股有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116554940-B | Oily corrosion inhibitor and preparation method thereof | 江苏太湖新材料控股有限公司 | 2023-11-03 | — | — | CN | disclosed |
| US-4087527-A | ANTIINFLAMMATORY AND ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4075206-A | ANTIINFLAMMATORY, ANTITHROMBOTIC | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4005074-A | Process for cleaving an imido side chain from penicillins and cephalosporins | ELI LILLY AND COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001239-A | CEPHALOSPORIN CLEAVAGE PROCESS | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3994888-A | Cephalosporin cleavage process | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111527-A1 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | ITPA, IMPA1, INTS9 | ALDH1A1 888/4885CYP3A4 475/4885TSHR 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.