Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 11/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355924 | 0.78 | — | — | |
| SCHEMBL28055684 | 0.78 | FDPS (0.45) | FDPSSMPD1TSHRGGPS1EPHX1 | |
| SCHEMBL21783109 | 0.78 | FDPS (0.45) | FDPSSMPD1TSHRGGPS1EPHX1 | |
| SCHEMBL12648605 | 0.77 | — | — | |
| SCHEMBL24355131 | 0.77 | FDPS (0.40) | FDPSSMPD1TSHRGGPS1EPHX1 | |
| SCHEMBL27845246 | 0.76 | FDPS (0.47) | FDPSSMPD1TSHRGGPS1EPHX1 | |
| SCHEMBL23156976 | 0.76 | FDPS (0.39) | FDPSSMPD1TSHRGGPS1 | |
| SCHEMBL28187132 | 0.75 | TSHR (0.40) | FDPSTSHRGGPS1EPHX1ADH1B | |
| SCHEMBL1410542 | 0.75 | TSHR (0.40) | FDPSTSHRGGPS1EPHX1ADH1B | |
| SCHEMBL18620869 | 0.74 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028492-A2 | SORTASE A INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-03-10 | — | — | WO | disclosed |