Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808554 | 0.76 | HTR1A (0.34) | — | |
| SCHEMBL14544251 | 0.75 | PTGS1 (0.43) | TSHRCYP3A4RECQLBLMHSD17B10 | |
| SCHEMBL8243337 | 0.75 | — | — | |
| SCHEMBL17313696 | 0.74 | TSHR (0.46) | TSHRGMNNUSP2CYP1A2POLB | |
| SCHEMBL17313694 | 0.74 | TSHR (0.46) | TSHRGMNNUSP2CYP1A2POLB | |
| SCHEMBL11328377 | 0.74 | — | — | |
| SCHEMBL7890396 | 0.72 | — | — | |
| SCHEMBL14586095 | 0.72 | — | — | |
| SCHEMBL11787779 | 0.70 | CYP1A2 (0.53) | TSHRGMNNUSP2CYP1A2POLB | |
| SCHEMBL13279845 | 0.70 | CYP1A2 (0.53) | TSHRGMNNUSP2CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173004-B2 | Macrocyclic isoquinoline peptide inhibitors of hepatitis C virus | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-06 | — | — | US | disclosed |