Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148564 | 0.92 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL14525262 | 0.67 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL930834 | 0.66 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL1305230 | 0.63 | — | — | |
| SCHEMBL14618444 | 0.63 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1 | |
| SCHEMBL13983462 | 0.62 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL8931047 | 0.62 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148481 | 0.60 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1 | |
| SCHEMBL1344531 | 0.60 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL17364290 | 0.57 | ADORA2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021877-A1 | IMIDAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2007-02-22 | — | — | WO | disclosed |