Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342870 | 0.91 | PDK1 (0.32) | — | |
| SCHEMBL14525258 | 0.80 | — | — | |
| SCHEMBL419121 | 0.77 | HSP90AA1 (0.35) | — | |
| SCHEMBL443161 | 0.73 | KDM4E (0.32) | — | |
| SCHEMBL14345177 | 0.72 | GAA (0.33) | — | |
| SCHEMBL1148483 | 0.71 | ESR1 (0.37) | — | |
| SCHEMBL419793 | 0.70 | KDM4E (0.47) | — | |
| SCHEMBL1344029 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL1147429 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL14136222 | 0.67 | HSP90AA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021877-A1 | IMIDAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2007-02-22 | — | — | WO | disclosed |