Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.55 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501657 | 0.88 | CCNT1 (0.64) | CCNT1KDM5AKDM4CKDM5B | |
| SCHEMBL1191606 | 0.87 | CCNT1 (0.64) | CCNT1KDM5AKDM4CKDM5B | |
| SCHEMBL30859471 | 0.86 | CCNT1 (0.58) | CCNT1KDM5AKDM4CKDM5B | |
| SCHEMBL12466193 | 0.84 | KDM5A (0.52) | KDM5AKDM4CKDM5B | |
| SCHEMBL1191651 | 0.84 | CCNT1 (0.68) | CCNT1KDM5AKDM4CKDM5B | |
| SCHEMBL1226111 | 0.82 | CCNT1 (0.54) | CCNT1KDM5AKDM4CKDM5B | |
| SCHEMBL12466322 | 0.81 | DYRK1A (0.46) | CCNT1KDM5AKDM4CKDM5B | |
| SCHEMBL12889499 | 0.79 | CCNT1 (0.77) | CCNT1 | |
| SCHEMBL1191967 | 0.77 | CCNT1 (0.66) | CCNT1 | |
| SCHEMBL30859468 | 0.77 | CCNT1 (0.80) | CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |