Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25712164 | 0.83 | MAPT (0.49) | AGXTMAOBTHRATHRBPARP10 | |
| SCHEMBL8639557 | 0.74 | AGXT (0.50) | AGXTMAOBTHRATHRBPARP10 | |
| SCHEMBL11698371 | 0.72 | MAOB (0.51) | AGXTMAOBTHRATHRBPARP10 | |
| SCHEMBL13925540 | 0.72 | THRA (0.50) | AGXTMAOBTHRATHRBPARP10 | |
| SCHEMBL17547997 | 0.72 | MAOB (0.53) | AGXTMAOBPARP10NPC1MAPT | |
| SCHEMBL11959895 | 0.71 | MAOB (0.67) | MAOBPARP10NPC1MAPTRAB9A | |
| SCHEMBL19604518 | 0.71 | MAOB (0.67) | MAOBPARP10NPC1MAPTRAB9A | |
| SCHEMBL10091327 | 0.70 | MAPT (0.55) | MAOBNPC1HTTMAPTTDP1 | |
| SCHEMBL17433295 | 0.70 | GAA (0.43) | AGXTMAOBPARP10NPC1MAPT | |
| SCHEMBL8929713 | 0.70 | MAOB (0.69) | AGXTMAOBPARP10NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946478-B1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES AND HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARMA INC (US) | 2007-02-14 | — | — | EP | disclosed |