Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.76 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045185 | 0.91 | CHRM2 (0.92) | CHRM2SCN8ALMNAL3MBTL1HDAC3 | |
| SCHEMBL10045186 | 0.89 | CHRM2 (0.88) | CHRM2SCN8ALMNAL3MBTL1HDAC3 | |
| SCHEMBL4913672 | 0.80 | CHRM2 (0.79) | CHRM2KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL5032223 | 0.80 | CHRM2 (0.79) | CHRM2KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL4917450 | 0.80 | CHRM2 (0.79) | CHRM2KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL8019471 | 0.79 | CHRM2 (0.82) | CHRM2SCN8AL3MBTL1HDAC3HDAC1 | |
| SCHEMBL4919923 | 0.78 | CHRM2 (0.75) | CHRM2LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL8328507 | 0.78 | CHRM2 (0.75) | CHRM2SCN8ALMNAKMT2AL3MBTL1 | |
| SCHEMBL12414383 | 0.78 | CHRM2 (0.75) | CHRM2LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL19449778 | 0.78 | CHRM2 (0.75) | CHRM2DRD2DRD4DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021839-A2 | POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS | JOHNS HOPKINS UNIVERSITY (US) | 2007-02-22 | — | — | WO | disclosed |