Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328363 | 0.98 | CHRM2 (0.79) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4262728 | 0.94 | CHRM2 (0.71) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL9672905 | 0.92 | CHRM2 (0.69) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8019471 | 0.89 | CHRM2 (0.82) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL3671076 | 0.88 | LMNA (0.61) | CHRM2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL4599034 | 0.86 | CHRM2 (0.64) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10045185 | 0.86 | CHRM2 (0.92) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10045186 | 0.84 | CHRM2 (0.88) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8326406 | 0.82 | CHRM2 (0.66) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL3668846 | 0.81 | MEN1 (0.65) | CHRM2MEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |