Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14009879 | 1.00 | LMNA (0.63) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1271236 | 0.86 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6277 | 0.86 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4164616 | 0.86 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8108955 | 0.86 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27882748 | 0.86 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL530337 | 0.86 | LMNA (0.67) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| Water SCHEMBL8429009 | 0.85 | LMNA (0.65) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28442347 | 0.85 | LMNA (0.65) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL887421 | 0.85 | LMNA (0.65) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173137-B2 | Epothilone analogs | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-06 | — | — | US | disclosed |