Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | IAPP | P10997 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073331 | 0.85 | HDAC1 (0.52) | HDAC1HDAC2LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL3803230 | 0.85 | HDAC1 (0.52) | HDAC1HDAC2LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7757786 | 0.85 | HDAC1 (0.52) | HDAC1HDAC2LMNAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8457834 | 0.84 | HDAC1 (0.51) | HDAC1HDAC2LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6015376 | 0.84 | HDAC1 (0.51) | HDAC1HDAC2LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6015374 | 0.84 | HDAC1 (0.51) | HDAC1HDAC2LMNAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8457836 | 0.84 | HDAC1 (0.51) | HDAC1HDAC2LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2154529 | 0.81 | HDAC1 (0.52) | HDAC1HDAC2MAPTCYP2C19HTT | |
| SCHEMBL15328886 | 0.81 | HDAC1 (0.49) | HDAC1HDAC2MAPTKDM4EKMT2A | |
| SCHEMBL14587959 | 0.81 | HDAC1 (0.49) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173137-B2 | Epothilone analogs | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-06 | — | — | US | disclosed |