Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015374 | 1.00 | HDAC1 (0.51) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| SCHEMBL3803230 | 0.98 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| SCHEMBL7757786 | 0.98 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| SCHEMBL2073331 | 0.98 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL8457836 | 0.96 | HDAC1 (0.51) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL8457834 | 0.96 | HDAC1 (0.51) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| SCHEMBL14619953 | 0.84 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| SCHEMBL1310629 | 0.79 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1GAAKDM4E | |
| SCHEMBL14587959 | 0.79 | HDAC1 (0.49) | HDAC1HDAC2 | |
| SCHEMBL15328886 | 0.79 | HDAC1 (0.49) | HDAC1HDAC2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439885-B1 | SIMPLIFIED SARCODICTYN DERIVATIVES AS ANTI-TUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2006-08-30 | — | — | EP | disclosed |
| US-20050038112-A1 | Simplified sarcondictyn derivatives as anti-tumor agents | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038112-A1 | Simplified sarcondictyn derivatives as anti-tumor agents | STOM, TTN, TNNC1 | HDAC1 2064/4885HDAC2 1309/4885ALDH1A1 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.