Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620065 | 0.79 | POLB (0.41) | MAOAMAOBPOLBKDM4EENPP3 | |
| SCHEMBL14620263 | 0.77 | MAOA (0.44) | MAOAMAOBPOLBKDM4EENPP3 | |
| SCHEMBL14620043 | 0.75 | NR1H2 (0.42) | SIRT2SIRT1MAPT | |
| SCHEMBL14620419 | 0.74 | NR1H2 (0.35) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6152442 | 0.73 | POLB (0.47) | POLBKDM4ESIRT2SIRT1ALDH1A1 | |
| SCHEMBL14620042 | 0.72 | COMT (0.39) | MAOBPRKDCALDH1A1MAPTGAA | |
| SCHEMBL12394337 | 0.71 | POLB (0.45) | MAOAMAOBPOLBKDM4ESIRT2 | |
| SCHEMBL12394320 | 0.70 | KDM4E (0.42) | POLBKDM4ESIRT2SIRT1ALDH1A1 | |
| SCHEMBL14063375 | 0.68 | CA12 (0.40) | MAOAMAOBPOLBKDM4ESIRT2 | |
| SCHEMBL6152233 | 0.67 | HPRT1 (0.45) | POLBKDM4ESIRT2SIRT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003520-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |