SCHEMBL14620111

SCHEMBL14620111

COc1cc(OC2CCCCC2)cc(OC2CCCCC2)c1N=N

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 3/20 0.45
PDGFRA P16234 3/20 0.45
PDE4A P27815 5/20 0.40
HIF1A Q16665 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PDE4B Q07343 6/20 0.38
PDE4D Q08499 5/20 0.38
PDE4C Q08493 4/20 0.38
MAPK14 Q16539 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
MAPT P10636 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14620110 0.97 PDGFRB (0.47) PDGFRBPDGFRAPDE4AHIF1AMEN1
SCHEMBL14588706 0.73 PDGFRB (0.45) PDGFRBPDGFRAPDE4AHIF1AMEN1
SCHEMBL14620452 0.72 ALDH1A1 (0.46) MEN1KMT2AMAPT
SCHEMBL14588705 0.72 PDGFRB (0.47) PDGFRBPDGFRAPDE4AHIF1AMEN1
SCHEMBL17639879 0.71 GRIN2D (0.42) PDGFRBPDGFRAPDE4AHIF1AMEN1
SCHEMBL27521810 0.69 PDE4A (0.60) PDE4AKMT2APDE4BPDE4DPDE4C
SCHEMBL16502110 0.68 HIF1A (0.48) PDGFRBPDGFRAPDE4AHIF1AMEN1
SCHEMBL5704547 0.67 PDE4A (0.57) PDE4APDE4BPDE4DPDE4CMAPK14
SCHEMBL26087169 0.67 ALDH1A1 (0.58) PDGFRBPDGFRAPDE4AHIF1AMEN1
SCHEMBL24806043 0.66 PDE4A (0.53) PDE4APDE4BPDE4DPDE4CPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157205-B2 Intermediate layer composition for multilayer resist process, pattern-forming process using the same, and laminate FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed