Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461741 | 0.73 | ALDH1A1 (0.48) | KMT2AMAPK1NPSR1ALDH1A1MAPT | |
| SCHEMBL1461584 | 0.69 | ALDH1A1 (0.34) | KMT2AMAPK1NPSR1ALDH1A1MAPT | |
| SCHEMBL21543246 | 0.67 | POLB (0.37) | KMT2AALDH1A1MAPTCYP1A2TDP1 | |
| SCHEMBL27227005 | 0.61 | MAPT (0.41) | ALDH1A1MAPTCYP1A2CYP2C9GAA | |
| SCHEMBL31020485 | 0.60 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL29427889 | 0.60 | MAPT (0.43) | KMT2AMAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL28929673 | 0.60 | MAPT (0.43) | KMT2AMAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL27365047 | 0.59 | ALDH1A1 (0.42) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL20516345 | 0.58 | ALDH1A1 (0.34) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL14183096 | 0.58 | GAA (0.50) | KMT2AMAPK1ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026891-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2011-03-10 | — | — | WO | disclosed |