Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918930 | 1.00 | ADRB3 (0.46) | ADRB3CYP19A1CACNA1FCHRM2ADRA2B | |
| SCHEMBL2056234 | 0.84 | MAPK1 (0.46) | ADRB3SLC6A4DRD3 | |
| SCHEMBL9908052 | 0.82 | TRPV1 (0.44) | ADRB3CYP19A1TRPV1NPC1RAB9A | |
| SCHEMBL6074905 | 0.81 | ADRB3 (0.53) | ADRB3CYP19A1 | |
| SCHEMBL7119142 | 0.81 | ADRB3 (0.53) | ADRB3CYP19A1 | |
| SCHEMBL2456888 | 0.81 | ADRB3 (0.53) | ADRB3CYP19A1 | |
| SCHEMBL14704484 | 0.79 | TRPV1 (0.41) | ADRB3CYP19A1TRPV1 | |
| SCHEMBL14704368 | 0.79 | TRPV1 (0.40) | CYP19A1TRPV1NPC1RAB9A | |
| SCHEMBL11918926 | 0.77 | THRA (0.44) | ADRB3CYP19A1NPC1RAB9A | |
| SCHEMBL12305628 | 0.77 | ADRB3 (0.74) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010356-A2 | PROCESS FOR THE PREPARATION OF SULFONAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2007-01-25 | — | — | WO | disclosed |