Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 2/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261222 | 0.92 | LMNA (0.40) | LMNAPTGIRPTGDR | |
| SCHEMBL12304458 | 0.84 | LMNA (0.60) | LMNASLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL22829337 | 0.83 | LMNA (0.42) | LMNASLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL9852714 | 0.83 | LMNA (0.63) | LMNASLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL12446343 | 0.82 | LMNA (0.38) | LMNASLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL13538559 | 0.80 | LMNA (0.47) | LMNAPOLB | |
| SCHEMBL4892711 | 0.80 | LMNA (0.41) | LMNASLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL17172522 | 0.79 | SLC1A3 (0.34) | LMNASLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL22856596 | 0.78 | LMNA (0.37) | LMNASLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL28479090 | 0.78 | PARP15 (0.38) | LMNASLC1A3SLC1A2SLC1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084170-B1 | POLYETHYLENE GLYCOL-POLYORTHOESTER, POLYETHYLENE GLYCOL-POLYORTHOESTER-POLYETHYLENE GLYCOL, AND POLYORTHOESTER-POLYETHYLENE GLYCOL-POLYORTHOESTER BLOCK COPOLYMERS | AP PHARMA INC (US) | 2007-01-17 | — | — | EP | disclosed |