Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639480 | 0.80 | ELANE (0.48) | ELANEPTGDR2 | |
| SCHEMBL9925305 | 0.79 | ELANE (0.50) | ELANEPTGDR2 | |
| SCHEMBL10063592 | 0.75 | ELANE (0.47) | ELANEPTGDR2 | |
| SCHEMBL20140783 | 0.75 | L3MBTL1 (0.63) | ELANELMNAPTGDR2 | |
| SCHEMBL14776567 | 0.74 | ELANE (0.46) | ELANE | |
| SCHEMBL6068638 | 0.74 | MAPT (0.47) | ELANELMNAPTGDR2 | |
| SCHEMBL30745084 | 0.74 | PDE5A (0.48) | ELANE | |
| SCHEMBL174888 | 0.74 | PDE5A (0.48) | ELANE | |
| SCHEMBL18058867 | 0.73 | ELANE (0.47) | ELANE | |
| SCHEMBL20140623 | 0.73 | ELANE (0.45) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002293-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |