Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA3 | P01011 | 1/20 | 0.51 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12339269 | 0.95 | SERPINA3 (0.48) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL14625843 | 0.95 | SERPINA3 (0.48) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL2734869 | 0.89 | SERPINA3 (0.48) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL14621490 | 0.89 | SERPINA3 (0.48) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL2734676 | 0.88 | POLB (0.52) | SERPINA3ADCY2POLBHDAC1HDAC2 | |
| SCHEMBL12339262 | 0.88 | POLB (0.46) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL14621775 | 0.88 | POLB (0.46) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL14621917 | 0.87 | SERPINA3 (0.46) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL12339272 | 0.87 | SERPINA3 (0.46) | SERPINA3ADCY2POLBHDAC1CDK1 | |
| SCHEMBL14621983 | 0.86 | SERPINA3 (0.46) | SERPINA3ADCY2POLBHDAC1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002808-A1 | ANTI-NONMELANOMA CARCINOMA COMPOUNDS, COMPOSITIONS, AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007002912-A2 | ANTI-PROLIFERATIVE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. (US) | 2007-01-04 | — | — | WO | disclosed |