Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.52 |
| ▸ | RXRA | P19793 | 12/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472563 | 0.93 | NR1H2 (0.57) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL14623308 | 0.84 | NR1H2 (0.46) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL3474288 | 0.83 | NR1H2 (0.60) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL3472959 | 0.79 | NR1H2 (0.57) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL27915620 | 0.77 | RXRA (0.55) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL3475132 | 0.77 | NR1H2 (0.72) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL3473105 | 0.77 | NR1H2 (0.61) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL2259556 | 0.75 | NR1H2 (0.62) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL3474026 | 0.74 | NR1H2 (0.61) | NR1H2NR1H3RXRACNR1LOXL2 | |
| SCHEMBL15641675 | 0.74 | NR1H2 (0.51) | NR1H2NR1H3RXRACNR1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002559-A1 | PYRAZOLE BASED LXR MODULATORS | EXELIXIS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |