Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472724 | 0.94 | GAA (0.51) | ATMALDH1A1GAAKDM4ECYP3A4 | |
| SCHEMBL3474130 | 0.87 | KDM4E (0.53) | ALDH1A1GAAKDM4ECYP3A4CYP2C9 | |
| SCHEMBL14622689 | 0.86 | MAPT (0.51) | ATMALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL3474999 | 0.80 | MAPT (0.54) | ATMALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL3472746 | 0.79 | RXRA (0.52) | SMN1; SMN2MAPTMEN1LMNAKMT2A | |
| SCHEMBL3471268 | 0.79 | KMT2A (0.56) | ALDH1A1GAAKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL3472034 | 0.78 | RXRA (0.51) | KDM4ESMN1; SMN2MAPTF10POLB | |
| SCHEMBL3471019 | 0.78 | RXRA (0.51) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL3475287 | 0.78 | KDM4E (0.55) | KDM4ECYP2C19SMN1; SMN2MAPTMEN1 | |
| SCHEMBL14624812 | 0.78 | TRPV1 (0.53) | SMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002559-A1 | PYRAZOLE BASED LXR MODULATORS | EXELIXIS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |