Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249939 | 0.81 | MEN1 (0.51) | MAPTLMNAPARP1CA12CA9 | |
| SCHEMBL14624379 | 0.80 | CHEK1 (0.51) | MAPTLMNAPARP1MEN1KMT2A | |
| SCHEMBL3249435 | 0.80 | MAPT (0.47) | MAPTLMNAPARP1MEN1KMT2A | |
| SCHEMBL15202149 | 0.79 | MAPT (1.00) | MAPTLMNAPARP1CA12CA9 | |
| SCHEMBL3250627 | 0.78 | MAPT (0.46) | MAPTLMNAPARP1CA12CA9 | |
| SCHEMBL14623778 | 0.78 | PARP1 (0.49) | MAPTLMNAPARP1CA12CA9 | |
| SCHEMBL14623074 | 0.78 | LMNA (0.49) | MAPTLMNAPARP1MEN1KMT2A | |
| SCHEMBL2545374 | 0.78 | CHEK1 (0.49) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL7251641 | 0.77 | PARP1 (0.66) | MAPTLMNAPARP1CA12CA9 | |
| SCHEMBL4161885 | 0.77 | PARP1 (0.45) | MAPTLMNAPARP1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | disclosed |