SCHEMBL1462385

SCHEMBL1462385

C=CC(=O)OC(C)(N)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.42
ALDH1A1 P00352 6/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.31
FGFR4 P22455 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10621305 0.96 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1561561 0.79
SCHEMBL3284091 0.79 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL187960 0.79
SCHEMBL28262319 0.79 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7712185 0.77 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20626572 0.77 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2740738 0.77 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3990177 0.77 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4419751 0.76 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080114128-A1 Synthesis of Copolymers in the Form of a Mikto Star by Controlled Radical Polymerization RHODIA CHIMIE (FR) 2008-05-15 US claimed
US-20220195077-A1 PROCESS FOR THE PREPARATION OF HIGH-SOLIDS, LOW-VISCOSITY LATEX USING SELECTIVE HYDROPHILIC MACRO-RAFT AGENTS SPECIALTY OPERATIONS FRANCE (FR) 2022-06-23 US disclosed
EP-3956372-A1 PROCESS FOR THE PREPARATION OF HIGH-SOLIDS, LOW VISCOSITY LATEX USING SELECTIVE HYDROPHILIC MACRO-RAFT AGENTS Rhodia Operations (FR) 2022-02-23 EP disclosed
WO-2020214553-A1 PROCESS FOR THE PREPARATION OF HIGH-SOLIDS, LOW VISCOSITY LATEX USING SELECTIVE HYDROPHILIC MACRO-RAFT AGENTS RHODIA OPERATIONS (FR) 2020-10-22 WO disclosed
EP-3512907-A1 METHOD OF PRODUCING POLYMER FILMS WITH GAS-BARRIER PROPERTIES BASF SE (DE) 2019-07-24 EP disclosed
EP-3510109-A1 SELF-THICKENING LATEX FOR WATERBORNE SYSTEMS AND RELATED METHODS Rhodia Operations (FR) 2019-07-17 EP disclosed
EP-3472212-A1 HIGH PERFORMANCE SURFACTANT FEE LATEXES FOR IMPROVED WATER RESISTANCE Rhodia Operations (FR) 2019-04-24 EP disclosed
EP-3328948-A1 COMPOSITIONS CONTAINING POLYANION, ETHOXYLATED CATIONIC POLYMER AND PHYLLOSILICATES FOR IMPROVED OXYGEN BARRIER COATINGS BASF SE (DE) 2018-06-06 EP disclosed
WO-2018050490-A1 METHOD OF PRODUCING POLYMER FILMS WITH GAS-BARRIER PROPERTIES BASF SE (DE) 2018-03-22 WO disclosed
WO-2018049135-A1 SELF-THICKENING LATEX FOR WATERBORNE SYSTEMS AND RELATED METHODS RHODIA OPERATIONS (FR) 2018-03-15 WO disclosed
US-20060217508-A1 Spray polymerization method BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 US disclosed
EP-1702108-A1 FILLER-CONTAINING PAPER AND A METHOD FOR THE PRODUCTION OF FILLER-CONTAINING PAPER BASF AKTIENGESELLSCHAFT (DE) 2006-09-20 EP disclosed
US-7012114-B2 Surface chemistry modified latex and redispersible powders, production and use thereof RHODIA CHIMIE (FR) 2006-03-14 US disclosed
WO-2005059249-A1 FILLER-CONTAINING PAPER AND A METHOD FOR THE PRODUCTION OF FILLER-CONTAINING PAPER BASF AKTIENGESELLSCHAFT (DE) 2005-06-30 WO disclosed
WO-2005059251-A1 POLYVINYLAMINE AS A WET STRENGTH RESIN BASF AKTIENGESELLSCHAFT (DE) 2005-06-30 WO disclosed
US-6809164-B2 FORMING LOW POLYDISPERSITY MATERIALS RHODIA CHIMIE (FR) 2004-10-26 US disclosed
US-20030114548-A1 Surface chemistry modified latex and resdispersible powders, production and use thereof RHODIA CHIMIE (FR) 2003-06-19 US disclosed
US-6506836-B1 Reacting under free-radical conditions a reaction mixture comprising at least one free-radically reactable monomer (a) in the presence of at least one free-radical initiator and of a compound process for preparing a polymer using said reaction BASF AKTIENGESELLSCHAFT (DE) 2003-01-14 US disclosed
US-5773545-A Polymers of alkyl-1-vinylimidazloes, the preparation and use thereof BASF AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
US-5194539-A Of ethylenically unsaturated monomers where the aqueous dispersion is free from odor causing xanthogen disulfide RHONE-POULENC CHIMIE (FR) 1993-03-16 US disclosed