SCHEMBL2740738

SCHEMBL2740738

C=CC(=O)OC(C)(C)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.45
ALDH1A1 P00352 5/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL1585650 0.98 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6928978 0.86 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL15313117 0.85 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3990177 0.85 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL23494179 0.85 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL14610245 0.83 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12428762 0.81 TSHR (0.38) TSHR
SCHEMBL23494160 0.81 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1887481 0.81 TSHR (0.38) TSHR
SCHEMBL19226797 0.81 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO claimed
CN-104536266-B A kind of dry film photoresist layered product 杭州福斯特应用材料股份有限公司 2018-08-07 CN claimed
US-7094860-B2 Maleimide group-containing polymer particles and method of producing the same FUJI XEROX CO., LTD. (JP) 2006-08-22 US claimed
US-20050014924-A1 Maleimide group-containing polymer particles and method of producing the same FUJI XEROX CO., LTD. (JP) 2005-01-20 US claimed
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO disclosed
CN-112980543-B High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity 英菲诺姆国际有限公司 2023-12-19 CN disclosed
CN-112980549-B High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity 英菲诺姆国际有限公司 2023-12-15 CN disclosed
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP disclosed
EP-3839019-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-08-02 EP disclosed
US-11685874-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2023-06-27 US disclosed
US-11384311-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
US-11365273-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-21 US disclosed
EP-1975712-A2 Positive resist composition and pattern forming method using the same FUJIFILM Corporation (JP) 2008-10-01 EP disclosed
EP-1471069-B1 Preparation of silyl ketene acetals and disilyl ketene acetals SHINETSU CHEMICAL CO (JP) 2007-04-18 EP disclosed
US-7112710-B2 Preparation of silyl ketene acetal and disilyl ketene acetal SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-09-26 US disclosed
US-20050256329-A1 Preparation of silyl ketene acetal and disilyl ketene acetal KIYOMORI AYUMU 2005-11-17 US disclosed
US-6960679-B2 Preparation of silyl ketene acetal and disilyl ketene acetal SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040215033-A1 Preparation of silyl ketene acetal and disilyl ketene acetal SHIN-ETSU CHEMICAL CO. LTD. (JP) 2004-10-28 US disclosed
EP-1471069-A1 Preparation of silyl ketene acetals and disilyl ketene acetals SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-10-27 EP disclosed
US-4048130-A COPOLYMERIZATION, UNSATURATED ACIDS LONZA LTD. (CH) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256329-A1 Preparation of silyl ketene acetal and disilyl ketene acetal TREH, DEGS1, PHYKPL TSHR 3406/4885ALDH1A1 678/4885TP53 4546/4885
US-20040215033-A1 Preparation of silyl ketene acetal and disilyl ketene acetal TREH, PHYKPL, KAT8 TSHR 3402/4885ALDH1A1 824/4885TP53 4200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.