Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 8/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779249 | 0.77 | NPC1 (0.46) | NPC1RAB9AMAPTKDM4EL3MBTL1 | |
| SCHEMBL13598047 | 0.74 | EGFR (0.64) | EGFRNPC1RAB9AMAPTKDM4E | |
| SCHEMBL14226047 | 0.68 | KMT2A (0.54) | EGFRNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL15635468 | 0.64 | ALDH1A1 (0.42) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL31241045 | 0.64 | KCNQ3 (0.53) | RAB9AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL2275255 | 0.63 | MEN1 (0.43) | RAB9AMAPTKDM4EPOLBL3MBTL1 | |
| SCHEMBL9204204 | 0.62 | CA12 (0.52) | NPC1RAB9AMAPTKDM4EPOLB | |
| SCHEMBL27468291 | 0.60 | MEN1 (0.51) | NPC1RAB9AMAPTTP53MEN1 | |
| SCHEMBL7934008 | 0.59 | TSHR (0.39) | NPC1RAB9AMAPTPOLBL3MBTL1 | |
| SCHEMBL6169811 | 0.59 | CCNK (0.46) | EGFRNPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007905-A2 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-18 | — | — | WO | disclosed |