Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19767370 | 0.94 | SLC6A4 (0.57) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL14625431 | 0.91 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2KCNH2CCR2 | |
| SCHEMBL1905855 | 0.82 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL19767369 | 0.82 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL19767367 | 0.82 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL19767371 | 0.82 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL7898806 | 0.79 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL19237328 | 0.76 | SLC6A2 (0.55) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL10043019 | 0.76 | SLC6A2 (0.55) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL436499 | 0.76 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2KCNH2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006546-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-01-18 | — | — | WO | disclosed |