Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.64 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19767369 | 1.00 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL19767371 | 1.00 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL14625431 | 0.90 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL14625009 | 0.82 | SLC6A4 (0.55) | SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL19767370 | 0.81 | SLC6A4 (0.57) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13279751 | 0.78 | AKR1C3 (0.57) | SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL19772413 | 0.78 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL13279749 | 0.78 | AKR1C3 (0.57) | SLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL3516082 | 0.78 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3516078 | 0.78 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868718-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARMACEUTICALS INC. (US) | 2018-01-16 | — | — | US | disclosed |